breakthrough-cancer-pain-6 subsys coupon

What is SUBSYS?


Titration With a Wide Range of Doses


Finding an Effective Dose: Titration with SUBSYS

How SUBSYS is Prescribed

Write SUBSYS units and doses to avoid confusion when prescribing the 1200 or 1600 mcg dose that require two units per dosage strength.

How SUBSYS is Supplied

SUBSYS offers the widest range of doses to find an effective dose.*

100 mcg dosage available in 10-pack cartons for simplified titration and dispensing.

SUBSYS 1200 and 1600 mcg dosages require 2 units per dose, and therefore contain 15 doses per carton.

Note: Colors are a secondary aid in product identification. Please confirm the printed dosage before dispensing. 

Doses Requiring 1 Spray

200 mcg, 400 mcg, 600 mcg, 800 mcg

Doses Requiring 2 Sprays

1200 mcg, 1600 mcg

* The Effective Dose was defined as the lowest dose that provided adequate analgesia, with tolerable adverse effects, over two consecutive episodes of breakthrough cancer pain.


  • If there is a need to titrate to a 200 mcg dose, prescribe 200 mcg SUBSYS units. Subsequent titration steps are 400 mcg, 600 mcg, 800 mcg, 1200 mcg, and 1600 mcg
Breakthrough Cancer Pain Relief
Breakthrough Cancer Pain Relief